Chronic fatigue studies
Fulvic and Humic Acids: Energy and Fatigue Reduction
Fulvic and humic acids, natural components of humus-rich soils and substances such as shilajit, play a crucial role in mitochondrial bioenergetics and fatigue reduction. These substances enhance energy generation at the cellular level, help mitigate symptoms of chronic fatigue, and promote physical endurance. The following peer-reviewed studies and articles support these claims.
1. Stimulation of Mitochondrial Respiration
- Title: Effect of humic substances on mitochondrial respiration and oxidative phosphorylation.
Conclusion: Fulvic and humic acids stimulate mitochondrial respiration and improve the efficiency of oxidative phosphorylation in vitro, especially after prolonged periods of contact with mitochondria.
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2. Increase in Energy and Reduced Fatigue
- Title: Mechanisms of action of humic substances as growth promoters in animals.
Conclusion: Humic and fulvic acid supplementation regulate mitochondrial bioenergetics, increasing the activity of key enzymes such as NADH dehydrogenase and ATP synthase, thereby improving energy and reducing fatigue in humans and animal models.
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3. Anti-fatigue composition
- Title: Anti-fatigue effect of OM-X, a plant extract fermented with lactic bacteria and bifidobacteria.
Conclusion: OM-X, which includes fulvic acid, reduces fatigue in healthy subjects after 12 weeks of supplementation.
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4. Reduction of Chronic Fatigue Symptoms
- Title: Shilajit attenuates behavioral symptoms of chronic fatigue syndrome.
Conclusion: Shilajit improves mitochondrial bioenergetics and modulates the HPA axis, mitigating symptoms of chronic fatigue in animal models.
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5. Energy and Physical Endurance
- Title: Energy and health benefits of Shilajit.
Conclusion: Shilajit, rich in fulvic acid, increases ATP production, ATP/ADP ratio and CoQ10, significantly improving energy and physical performance.
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6. Conservation of Muscle Strength
- Title: The effects of Shilajit supplementation on fatigue-induced decline in muscle strength.
Conclusion: Shilajit supplementation reduces muscle strength loss and improves connective tissue integrity after intense exercise.
Link: Read more
General Summary
Fulvic and humic acids act as powerful modulators of cellular energy, reducing fatigue and improving physical endurance. Their antioxidant action and ability to preserve mitochondrial function position them as effective natural supplements for people looking to improve their energy, physical performance and recovery.
