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Diabetes Studies

Conclusion: Fulvic acid may help prevent chronic inflammatory diseases, including diabetes.

Title: Therapeutic potential of fulvic acid in chronic inflammatory diseases and diabetes

Document Type: Peer-Reviewed Journal Article

Conclusion: Traditional medicine and modern research claim that fulvic acid (FA) can modulate the immune system, influence the oxidative status of cells, and improve gastrointestinal function; all of which are hallmarks of diabetes. This mini-review describes the available peer-reviewed research on FA and examines its anecdotal health claims. We show that although the available research has been minimal, there is substantial evidence for continued FA research in the prevention of chronic inflammatory diseases, including diabetes.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151376/

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Conclusion: Fulvic acid may help maintain blood sugar levels.

Title: Preparation of medical fulvic acid standard substance and application of medical fulvic acid standard substance in cell experiments

Document Type: Patent

Conclusion: Humic acid is subjected to catalytic oxidation of humic acid over peat, lignite and weathered coal, deep separation by vertical cyclone machine, horizontal screw separator and disc centrifuge, ash removal by gel phase change, continuous desalination by hydroalcoholic membrane, homogeneous and heterogeneous electrodialysis membranes, and molecular weight determination to obtain medical standard substance of fulvic acid; and by hepatoma cell Hep1-3B transaminase inhibition experiment; The compound reacts with alpha-glucosidase, is used for experiments on preventing pancreas from resisting and reducing blood sugar, the survival rate in human brain U87 glioma cells is verified, has a pharmacological effect of 35.28-80.00% or more, has an adjusting effect on the brain barrier, effectively improves the additional value of fulvic acid pharmaceuticals, and has a broad application prospect.

Link: https://patents.google.com/patent/CN113736098A/en?q=fulvic+acid+health&oq=fulvic+acid+health&page=1

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Conclusion: Shilajit may help control blood glucose levels in diabetes.

Title: Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats

Document Type: Peer-Reviewed Journal Article

Conclusion: In diabetic rats, all three doses of shilajit produced a significant reduction in blood glucose levels and also produced beneficial effects on lipid profile. The maximum effect was observed with 100 mg/kg/day dose of shilajit. The combination of shilajit (100 mg/kg) with glibenclamide (5 mg/kg/day) or metformin (0.5 g/kg/day) significantly enhanced the glucose-lowering ability and improved the lipid profile than either of these drugs given alone. Thus, shilajit is effective in controlling blood glucose levels and improves the lipid profile.

Link: http://www.ijp-online.com/article.asp?issn=0253-7613;year=2004;volume=36;issue=6;spage=373;epage=376;aulast=Trivedi

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Conclusion: Fulvic acid can reduce blood glucose levels and improve lipid metabolism in diabetes.

Title: Hypoglycemic effect of fulvic acid and sodium fulvate in diabetic mice

Document Type: Peer-Reviewed Journal Article

Conclusion: Medium and high doses of fulvic acid and sodium fulvate can significantly reduce blood glucose of normal mice; Medium and high doses of fulvic acid and sodium fulvate can significantly reduce blood glucose, total cholesterol (TC) and triglyceride (TG) levels of diabetic mice. It is concluded that fulvic acid and sodium fulvate can significantly reduce blood glucose, TC and TG levels of mice and increase oral glucose tolerance of mice. This indicates that fulvic acid and sodium fulvate have hypoglycemic activity and can improve lipid metabolism of diabetes.

Link: http://en.cnki.com.cn/Article_en/CJFDTOTAL-KMLG201105012.htm

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Conclusion: Fulvic acid may help regulate blood sugar levels and reduce cholesterol in diabetic patients.

Title: Fulvic acid or sodium fulvate substance with hypoglycemic function.

Document Type: Patent

Conclusion: The invention relates to a health care product and a medicament, in particular to a health care product with fulvic acid or sodium fulvate substance and a medicament with hypoglycemic function; fulvic acid or sodium fulvate substance with hypoglycemic function is provided, in particular to the health care product, and the health care product is an oral solution, the ingredients of the oral solution are as follows in mass percentage: 1-10 percent of fulvic acid or sodium fulvate, 0.5-10 percent of polysaccharide sulfate, and the remainder is water; the health care product, fulvic acid or sodium fulvate substance, can remarkably reduce the blood sugar, total cholesterol and triglyceride content of diabetics, increase oral carbohydrate tolerance, and has the function of regulating blood sugar level; Fulvic acid or sodium fulvate substance health care product is a purely natural product, it is safe and reliable and has no toxic or side effects, so it is the health care product that can meet people's needs.

Link: https://patents.google.com/patent/CN101744844B/en?q=fulvic+acid+health&oq=fulvic+acid+health&page=2

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Conclusion: Shilajit may prevent maturity-onset diabetes.

Title: Shilajit attenuates streptozotocin-induced diabetes mellitus and decreased pancreatic islet superoxide dismutase activity in rats

Document Type: Peer-Reviewed Journal Article

Conclusion: The findings confirm previous observations that STZ-induced hyperglycemia may result from decreased pancreatic islet superoxide dismutase activity, leading to free radical accumulation and β-cell damage. Shilajit attenuates both effects of STZ possibly by its action as a free radical scavenger. The findings support the postulate that shilajit may prevent maturity-onset diabetes mellitus.

Link: https://sci-hub.hkvisa.net/10.1002/ptr.2650090110

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